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Toxins (Basel) 2021;13(6):401

BioID pull-downs were done using Streptavidin Dynabeads (Invitrogen, Cat#65001) as described 73 , and protein was eluted from the beads by boiling for 15 min in LDS sample buffer (Invitrogen, Cat#NP0007)

This may potentially impact lipid oxidation, modulating oxylipin synthesis as vitamins A, B, E, and K have been shown to decrease or prevent lipid peroxidation, thereby inhibiting ferroptosis (Shastak et al., 2023

Rather than relying on assumptions or genetic results alone, a more evidence-based approach is to assess functional biomarkers such as homocysteine and interpret these alongside the wider clinical picture