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Description

Recently, Guan et al found that patients with severe AH exhibited significantly higher IL-8-positive neutrophils in the liver compared with patients with alcohol-associated liver cirrhosis, contributing to persistent inflammation

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beyond the plasma membrane (FSP1) and mitochondria (DHODH), the specific antioxidant mechanisms in organelles such as the endoplasmic reticulum (a major site of lipid synthesis) and peroxisomes (involved in lipid oxidation) are poorly defined, and their crosstalk with cytoplasmic SOD/CAT remains elusive

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As visceral fat decreases, lean body mass is maintained or modestly improved a key advantage over calorie restriction, which often causes muscle loss alongside fat loss

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