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The rationale was that direct delivery to the joint would maximize local efficacy while minimizing systemic exposure

Management of Hypothyroidism The main treatment of hypothyroidism includes adding synthetic hormones to ones body to replace the thyroid hormone deficiency

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A prenatal vitamin should include B12, but since it is a key nutrient during pregnancy (contributing to fetal development, among other things), pregnant women who are vegan or have another reason to suspect a deficiency should talk to their doctor

This can be done by eating foods such as meat, fish, dairy products, and eggs, or by taking vitamin B12 supplements if prescribed by a doctor