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L.RamayyaA

10.1016/j.canlet.2016.02.021 55 KimuraT.JainA.ChoiS

Stochastic state transitions give rise to phenotypic equilibrium in populations of cancer cells

Defects occur in both the NADPH oxidase complex itself and the enzymes of the PPP that yield the required NADPH, particularly G6PDH The Pentose Phosphate Pathway The pentose phosphate pathway (PPP) (also called hexose monophosphate shunt, HMS) consists of series of interconnected reactions that serve as an alternate route for the metabolism of glucose

In summary, as a critical component in AD pathology, mechanistic investigation and therapeutic exploration of ferroptosis hold significant importance, necessitating further multidimensional and interdisciplinary research to comprehensively understand its relationship with AD and drive innovative treatment development