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First, at the mechanistic level, single-cell spatial transcriptomics and metabolomics should be used to map ferroptosis pathways in nigral dopaminergic neurons, astrocytes, and microglia, with emphasis on the interplay between NCOA4-mediated ferritinophagy and -synuclein degradation, to build a dynamic model linking iron dysregulation, proteotoxic stress, and cell death

Zimta AA, Cenariu D, Irimie A, Magdo L, Nabavi SM, Atanasov AG, Berindan-Neagoe I

alkyne and no-alkyne control indicate the two REX-probes used for differential enrichment proteomics workflow

Debatri Datta, MBBS, MD Dermatology , Venereology & Leprosy Skin Whitening Injections: Skin whitening injections contain glutathione, a skin lightening agent that minimises the production of an enzyme called tyrosinase, which increases the melanin levels