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Tetrahydrofolate (THF) serves as a universal one-carbon acceptor and can accept one-carbon from the conversion of serine to glycine (folate cycle), the oxidation of glycine to CO 2 and NH 3 by the glycine cleavage system (GCS) 6 or methionine to homocysteine conversion (methionine cycle) 59

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Endocrinol Exp 10(4):289295 Guan ZZ, Zhuang ZJ, Yang PS, Pan S (1988) Synergistic action of iodine deficiency and fluorine intoxication on rat thyroid

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