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Role in Renal Anemia In renal disease, endothelial NO synthase (eNOS) activity is reduced due to uremic toxins and oxidative stress, leading to decreased NO bioavailability (Owusu et al., 2012)

Elimination and Excretion 3.5.4.1

Transmission electron microscopy Cells were digested with 0.25% trypsin and 0.02% EDTA, washed with Hanks Balanced Salt Solution (HBSS)

*Correspondence: Fatemeh Atyabi, [email protected] Present address: Meshkat Dinarvand, Image-Guided and Functional Instructed Tumor Therapy (iFIT), University of Tuebingen, Tuebingen, Germany These authors share first authorship This article was submitted to Molecular Diagnostics and Therapeutics, a section of the journal Frontiers in Molecular Biosciences Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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