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The thresholds reported in preclinical literature vary: PCB-157 : 10 g/kg to 1 mg/kg subcutaneously or intraperitoneally depending on the model

Am J Physiol 290(4):G747G756 Shimomura Y, Harada M, Goto M, Sugo T, Matsumoto Y, Abe M et al (2002) Identification of neuropeptide W as the endogenous ligand for orphan G-protein-coupled receptors GPR7 and GPR8

Radiation necrosis (RN) may occur from months to years following treatment, affecting a reported 324% of patients [13]

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Those that had no pre-existing tattoos experienced a greater strain on their immune system, observed by a larger dip in their SIgA