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When to reassess If GI symptoms worsen instead of improving over the first 2-3 weeks, if any unusual symptom appears, or if blood glucose readings drop more than expected, pause and consult a qualified clinician

Poor blood supply slows the rate at which fibroblasts and other wound-healing cells can reach the area of injury and, ultimately, restricts the overall level of repair that can take place

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Supporting this possibility, blood levels of BDNF significantly declined during chronic cocaine exposure but tended to increase during early abstinence [14, 15]