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Vitamin C suppresses ovarian pathophysiology in experimentalpolycystic ovarian syndrome

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Lee KM, Kim YS, Seo GS, Kim TO, Yang SK

We propose that these factors act synergistically in immune cells to drive aberrant inflammation in both the CNS and the periphery in PD, contributing to a hostile inflammatory environment which renders certain subsets of neurons vulnerable to degeneration

Manganese superoxide dismutase (MnSOD) converts O 2 to H 2 O 2 , which can then be reduced to H 2 O by catalase and/or an antioxidative system comprised of gluthione, gluthathione peroxidases (Gpx), peroxiredoxins (Prx), and thioredoxins (Trx), dependent on the redox status and availability of reducing equivalents within mitochondria [5859]