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Former FDA Commissioner Marty Makary who resigned in May was also highly critical of FDA advisory panels, complaining that they were expensive, time-consuming and subject to too many financial conflicts

However, in the United States, lacking definite data about susceptibility to clarithromycin, metronidazole, and levofloxacin, we should assume resistance is present and use a 4-drug regimen (eg, concomitant therapy or bismuth quadruple therapy)