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Nitroglycerin metabolism in vascular tissue: role of glutathione S-transferases and relationship between NO

Gene expression analysis was performed by RT-PCR using the Quanti Nova SYBR green PCR kit (Qiagen, Valencia, CA, USA)

Smad7 has a myocardial protective effect, and its overexpression could reverse Smad3-mediated myocardial fibrosis and nuclear factor kappa B (NF-B)-driven inflammation (Frangogiannis, 2022