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10.1038/s41467-020-19193-y 206 YiJ.ZhuJ.WuJ.ThompsonC

Some patients find the other complaints resolve on their own once sleep is addressed

Two Systems Control Growth Hormone Release Dual regulation of growth hormone secretion showing hypothalamic GHRH signalling and ghrelin receptor activation in the pituitary, leading to GH pulses that stimulate IGF-1 production in the liver and muscle protein synthesis

The growth hormones role is vast in that it is directly correlated with healthy metabolism, lower levels of fat accumulation, heart health, exercise capacity, maintenance of muscle, as well as cognitive function