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Selective killing of cancer cells by a small molecule targeting the stress response to ROS

10.3390/ijms22147697 195 KislerK.SagareA

In contrast, the study of GSH-Pxs in prokaryotes remains underexplored, and they have been reported only in Streptococcus pyogenes , where a gsh-px mutant was associated to an impaired virulence in mice infection models [13]

Grx1 has garnered much interest due to its similarity with Trx1 in promoting cytosolic protection, yet Grx2 with its primary mitochondrial localization may hold a crucial role in preventing cell death

Increased mortality in haemodialysis patients administered high doses of erythropoiesis-stimulating agents: a propensity score-matched analysis