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Athletes may have blood, dried blood spot, urine, and/or other WADA-approved samples collected at an event (in-competition testing) or at another location (out-of-competition testing.) Test Distribution Planning (TDP): Through the TDP process for both in- and out-of-competition testing, USADA works collaboratively with a number of entities to determine: How many tests will be collected Which athletes will be tested When testing occurs If urine, blood, and/or dried blood spot will be collected What special analysis may need to be performed on the samples Doping Control Officers : USADA has more than 60 highly trained Doping Control Officers (DCOs) stationed throughout the world

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Furthermore, Xe was shown to influence the methylation of endogenous -secretase (BACE1) and low-density lipoprotein receptor-related protein 1 (LRP1), both of which are closely related to amyloid- (A) production (47)

Blaser, 2011