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Ferroptosis, a recently discovered form of regulated cell death (RCD), is characterized by iron dependence, lipid peroxidation, increased reactive oxygen species (ROS), and disruption of mitochondrial metabolism [14, 15]

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IgG form patients with pulmonary arterial hypertension and/or systemic sclerosis binds to vascular smooth muscle cells and induces cell contraction

Repeat reactions during the same treatment are possible in some extreme cases but are rare

It appears to function as a biological signaling peptide that helps coordinate repair processes throughout the body.