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Las pastillas y los polvos pasan con dificultad por el sistema digestivo, perdiendo su eficacia

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Extracellular signaling Even though mostly executing their functions intracellularly, there is a substantial portion of extracellular HSP70s released in endolysosomes, together with such proteins as cathepsin D and LAMP1 with the help of ATP-binding cassette transporters (Mambula et al., 2007), exosomes (Takeuchi et al., 2015) and microvesicles (Komarova et al., 2021)

This intricate interplay between the nervous system and GBM adds an extra aspect of complicity to understanding the TME and its impact on cancer progression [331]