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Description

Phase I studies from the late 1980s using IGF-1 to treat Larons Syndrome (GH insensitivity) revealed effective increase in linear growth reaching adult heights using doses ranging from 80 to 240 g/kg/day [264268]

Costs depend on your dosing level and supplier

Images were analyzed using the Adiposoft plug-in software in ImageJ (NIH)

In experimental models, researchers may explore processes such as hypothalamicpituitary axis signaling dynamics, insulin-like growth factor-1 (IGF-1)associated pathways, and downstream metabolic signaling mechanisms