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10.1007/s10549-021-06454-7 Breast Cancer Res Treat

This alteration in aspirin antithrombotic effect is speculated to result from decreased carboxylesterase activity in the gut by oral ampicillin, reducing some enterococci, enterobacteria, and lactobacilli strains, decreasing the pre-systemic conversion of aspirin to salicylic acid, and increasing its absorption and systemic effects [29, 85]