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The building block were trifunctional with one free -COOH reactive group, one Ns-protected amine and one Msec-protected amine

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In addition, the CTH inhibitor has off-target activity (33, 40)

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FIGURE 3 L-Theanine and Mg-L-Theanine Compounds Reverse Caffeines Effect on Glutamate Receptors To elucidate the effects of L-theanine and Mg-L-theanine on the glutamatergic receptors, we measured glutamatergic AMPA receptor GluA1, and glutamatergic NMDA receptors GluN1, and GluN2a levels with Western blotting