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To understand the potential effect of the ferroptosis pathway in the EMFF group, Gene Set Enrichment Analysis (GSEA) was performed to assess the expression levels of genes involved in the progression of ferroptosis in the EMFF group (Fig

Physiopathological functions of GPx and associated diseases The increase of ROS has been associated with the appearance and progression of aging and related diseases including arthritis, diabetes, dementia, cancer, atherosclerosis, and vascular diseases, which are inflammatory disorders, a consequence of oxidative stress [54, 55]