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The economic consequences extend beyond healthcare, impacting resources that could otherwise be directed toward development and improving living conditions

Thus, by examining this angle, we aim to reveal the mechanism by which FOXO4-DRI alleviates individual aging, providing a new perspective for the treatment of aging using FOXO4-DRI

(2) the central nucleotide-binding and oligomerization (NACHT) domain, and (3) the amino-terminal pyrin domain (PYD) that mediates protein-protein interactions (Unterberger et al., 2021)