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A thermostable oxidation-reduction system (Hopkins FG, Dixon M (1922) J Biol Chem 54 527563)

indeed, some tumors use fatty acid oxidation (FAO) as the main source of energy and express high levels of FAO enzymes

reported that methionine supplementation enhances T cell response in a small cohort of colorectal cancer patients oral supplement at 1000 mg/day for two weeks significantly improved CD8+ T cell cytokine production and reduced T cell apoptosis, highlighting the potential for clinical translation ( Manipulating GCN2 to enhance T cell anti-tumor immunity GCN2 plays a crucial role in regulating T cell immunity, particularly in amino acid-limited conditions and indoleamine 2,3-dioxygenase (IDO)-mediated immune suppression (105, 109, 110, 112)