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Sikiric et al., 2003

doi: 10.1016/j.cyto.2017.05.023 118 WengnerAMHpkenUEPetrowPKHartmannSSchurigtUBruerRet al

Cycling AOD-9604: Duration, Breaks, and Receptor Sensitivity Typical AOD-9604 research protocols run 1224 weeks, mirroring the clinical trial durations that generated the primary efficacy data

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2 2) Modulation of the nitric-oxide (NO) system & vascular tone Ex vivo aorta studies show BPC-157 modulates vasomotor tone in an NO-dependent manner, likely via SrcCav-1eNOS interactions that increase NO generation