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Polis S, Fernandez R

Doc Ophthalmol Adv Ophthalmol

Natural evolution has been a springboard for directed or experimental evolution, serving both as a reservoir of methods to be mimicked and of molecular templates to be mutagenized

Identification of brain metastasis genes and therapeutic evaluation of histone deacetylase inhibitors in a clinically relevant model of breast cancer brain metastasis

Pharmacokinetically, curcumins limited oral bioavailability due to poor solubility and extensive hepatic metabolism has prompted the development of enhanced formulations, including liposomal, nanoparticle, and piperine-adjuvanted forms, all of which demonstrate greater systemic absorption and target tissue delivery