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As other GSTF members bearing a conserved serine in the active site motif, enzymatic analysis showed that GSTF1 possesses glutathione-conjugating activity toward structurally diverse substrates and glutathione peroxidase activity

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Gourley C, Michie CO, Roxburgh P, Yap TA, Harden S, Paul J et al

Of the three amino acids that constitute glutathione, low levels of cysteine compared to a relative abundance of glutamine and glycine often limits your ability to produce the master antioxidant

Finally, we explored the potential interaction mechanisms between gut microbial metabolites and GPX3 protein through molecular docking and molecular dynamics simulation analyses