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Persistent symptoms should always be evaluated by a spine specialist

2018;17(4):e12768 22

67,68,69 The proportion of the CD14 + CD16 + subset of monocytes was elevated with downregulated expression of CX3CR1 and HLA-DRA during aging, whereas the CD14 + CD16 - subset was decreased

Side effects such as upper respiratory infection, low white blood cell count, and suicidality necessitate more extensive trials to confirm safety (Papp 2012