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IVC, inferior vena cava

Salvianolate, a compound derived from Salvia miltiorrhiza extracts and primarily composed of salvia magnesium acetate, has been demonstrated to mitigate contrast-induced AKI while alleviating OS associated with podocyte injury (Liang et al., 2021)

In most studies, CYP activation is described as an upstream event leading to the production of reactive metabolites, which are themselves responsible for DNA adduct formation

Chik CL, Friedman A, Merriam GR, Gahl WA (1993) Pituitary-testicular function in nephropathic cystinosis

For example, it participates in gene transcription regulation by acetylating transcription factors such as p53 and STAT3, which modulates their DNA-binding affinity and transcriptional activity (Narita et al., 2019)