mechanism of action of tobacco Biological determinants impact the neurovascular toxicity nicotine and smoke: A pharmacokinetic and pharmacodynamics perspective Tobacco Smoke Induces and Alters

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Anderson C, Majeste A, Hanus J, Wang S (2016) E-Cigarette aerosol exposure induces reactive oxygen species, DNA damage, and cell death in vascular endothelial cells

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For these cells, high expression of miR-125a-5p enhances activation of the SIRT1/HIF-1 signaling pathway through Sp1 and promotes their senescence