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Acetaldehyde, a toxic by-product, contributes to symptoms such as nausea, vomiting, facial flushing, and increased heart rate

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"There's a persistent myth that adding tobacco to cannabis will make you more stoned, but we found that actually, it does nothing to improve the subjective experience," said the study's lead author, Chandni Hindocha (UCL Clinical Psychopharmacology Unit)

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THC and THC-COOH concentrations were considered as independent variables, and the 70 variables of the extended steroid profile dataset were used as X-independent variables (THC-model M2 in Supplementary Section S4