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As we age, collagen production slows down

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It plays a key role in cellular signaling, particularly in response to certain growth factors and cytokines

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J Biol Chem 179:12451254 Carmel-Harel O, Storz G (2000) Roles of the glutathione- and thioredoxin-dependent reduction systems in the Escherichia coli and Saccharomyces cerevisiae responses to oxidative stress