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Together, these findings indicate that smoking even a small number of cigarettes per day has substantial negative health effects and provide further evidence that smoking cessation benefits all smokers, regardless of how few cigarettes they smoke. About the National Cancer Institute (NCI): NCI leads the National Cancer Program and the NIHs efforts to dramatically reduce the prevalence of cancer and improve the lives of cancer patients and their families, through research into prevention and cancer biology, the development of new interventions, and the training and mentoring of new researchers

Cigarette butts are the worlds most frequently littered item, and tobacco filters (made of cellulose acetate) constitute the number one ocean plastic, more numerous than plastic bottles, bags, or straws

They get scared of withdrawal symptoms and cravings, which leads to repeated failed attempts

doi: 10.3389/fpubh.2025.1531268 Received 20 November 2024 Accepted 11 June 2025 Published 07 July 2025 Volume 13 - 2025 Edited by Christiane Stock, Charit Universittsmedizin Berlin, corporate member of Freie Universitt Berlin and Humboldt-Universitt zu Berlin, Germany Reviewed by Donald Reed, Liberty University, United States Venkat Kumar, SRM Institute of Science and Technology, India Updates Copyright 2025 Sekaran, Ganapathy, Arumuganainar, Arumugasamy, Selvaraj, Alassiri and Abullais

Milbemycin falls in the middle because it is safer than high dose ivermectin but not as effective