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For example, monomers of flavonoid compounds are difficult to extract and have poor lipid solubility and low bioavailability, limiting their clinical applications [96]

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Refrain from applying products that might have salicylic acid or AHAs

Deoxyarbutin and its second-generation derivatives have been proposed as promising agents to ameliorate hyperpigmented lesions or lighten skin due to less toxicity at their effective inhibitory dose 185 , 186

Additionally, emerging evidence highlights the importance of gut microbiota in the immune-endocrine regulation of endometriosis, suggesting a potential role for prebiotics, probiotics, and dietary fiber in restoring microbial homeostasis and improving clinical outcomes [17]