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Moreover, lipid peroxidation products may contribute to hepatic dysfunction and the development of MASLD through mechanisms involving inflammation and the dysregulation of insulin signaling

BNIP3 is a member of the BH3-only subfamily whose expression is promoted by HIF-1 transcriptional activity

Ferroptosis is characterized by the depletion of intracellular GSH and decreased activity of GPx4, which in turn results in the accumulation of lipid peroxides and Fe(II)-catalyzed oxidation of lipids by the Fenton reaction and increased ROS formation

ALA can synergistically enhance blood glucose uptake, thereby potentially causing blood sugar to drop more than expected

Pentoxifylline plus ACEIs/ARBs for proteinuria and kidney function in chronic kidney disease: a meta-analysis