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(2006) HIV-1-induced pulmonary oxidative and nitrosative stress: exacerbated response to endotoxin administration in HIV-1 transgenic mouse model

Martens, C.J

Caspase-1 cleaves gasdermin D (GSDMD), whose N-terminal fragment forms pores in the plasma membrane, leading to cell lysis and the release of proinflammatory cytokines such as interleukin 1 beta (IL1B), IL-18, and IL1A [70]