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doi: 10.1016/j.ese.2022.100205 5 AbdelfattahA.HossainA

Collectively, these interlinked mechanisms demonstrate that the Nrf2-Keap1 and NLRP3 pathways form a dynamic regulatory axis in PD, in which redox balance mitochondrial integrity and inflammatory signaling are tightly coupled

Furthermore, significant accumulation of TZ in the brain following administration indicates its ability to cross the bloodbrain barrier, highlighting its considerable promise for PD treatment [183]

Predicted aligned error plots (top) and predicted LDDT (local distance difference test) plots (bottom) of human (left) and yeast (right) AlphaFold models

Images of human body and cells was created using Microsoft Copilot AI