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On day 4, the medium was switched to Neurobasal medium (Gibco) supplemented with 2% B27 (Gibco), 0.5% MEM Non-Essential Amino Acids, 1.5% D-(+)-glucose, 1% GlutaMAX, and 0.2% Normocin

The unique formulation of Migraine Clear includes riboflavin, a common B vitamin that has been shown to be an effective prophylactic in the prevention of migraines and magnesium which is believed to impact migraines by its vasodilitory, calcium channel blocking, and possible reduction of reperfusion dysfunction activity which may benefit vascular headaches and muscle tension headaches

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More recently, a limited number of studies have indicated a direct association between GM and blood pressure control in animal models (Yang et al., 2015)