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Yau et al., 2019

Goldstein, JA., Betrayal by the Brain: The Neurologic Basis of Chronic Fatigue Syndrome, Fibromyalgia Syndrome, and Related Neural Network 2012 Haworth Medical Press

In radioresistant SW837 cells, the addition of metformin to 1.8 Gy induced a significant G0/G1 arrest at 6 h and 10 h post irradiation, when compared to irradiated vehicle control ( Figure 2D )

At the titrated once-daily doses, roughly one vial covers a 34 week phase at these once-daily doses, so plan several vials for a full course

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