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The observer is usually not able to guarantee that all animals tested will respond as their physiological and olfactory pre-exposure state is unknown ( Figure 2A shows the effects of removing non-responding shore crabs ( C

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Graves orbitopathy (GO) is the most prominent and common extrathyroidal manifestation of GD, characterized by the production and accumulation of glycosaminoglycans (especially hyaluronic acid) in the retrobulbar and periorbital tissues causing protrusion of the eyeball and restriction of ocular muscle movement ( Table 1