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Dan Wool, NMD Arizona-licensed Naturopathic Physician, Hormone, Peptide & Gastroenterology Specialist Updated: February 27, 2026 Summary: What Is Epithalon Peptide?: Epithalon is a synthetic four-amino-acid peptide modeled after pineal gland compounds that may activate telomerase to maintain telomeres, support circadian rhythms and melatonin production, though human research remains limited and mostly preclinical

Researchers have examined its interaction with pathways associated with nitric oxide signaling, endothelial function, and extracellular matrix repair

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doi:10.1016/j.enzmictec.2004.08.003 Wen S, Zhang T, Tan T (2005) Optimization of the amino acid composition in glutathione fermentation