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People have trouble dealing with stress, because their primary coping response has become using nicotine, Piper says

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(The District of Columbia has the highest tax at $4.50 and Missouri has the lowest at 17 cents.)6-8 Cigars, pipe tobacco products and smokeless tobacco, other than snuff, are taxed at 80% of the wholesale coast

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Neuropsychopharmacology 31 , 431441 (2006)