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[DOI] [PubMed] [Google Scholar] 2.Sikiric P., Udovicic M., Barisic I., Balenovic D., Zivanovic Posilovic G., Strinic D., Uzun S., Sikiric S., Krezic I., Zizek H., et al

Sirtuins Sirtuins (SIRT1SIRT7) are NAD-dependent class III HDACs that regulate autophagy through histone deacetylation and nonhistone protein modification

These components play crucial roles in breaking down fats, enhancing metabolism, and promoting overall vitality

These studies all indicate that combined therapeutic strategies integrating multiple active components through hydrogels show significant advantages over single therapies, making hydrogels a promising biomaterial in IDD treatment