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doi: 10.3389/fendo.2020.614981 Received 07 October 2020 Accepted 31 December 2020 Published 23 February 2021 Volume 11 - 2020 Edited by Karine Rizzoti, Francis Crick Institute, United Kingdom Reviewed by Paul Le Tissier, University of Edinburgh, United Kingdom

PubMed Central , Frontiers in Endocrinology , vol

For example, downregulated SIRT5 increases glutarylation levels of CPS1 under nutrient-deprived conditions

They are pathway-level traits, not predictions: the genetic test never forecasts response to any specific compound, and it is not a drug-response predictor