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On the left, the riboflavin-dependent enzyme glutathione reductase converts oxidized glutathione (GSSG) into two molecules of reduced glutathione (GSH)

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In severe acute pancreatitis (SAP), inflammatory factors promote the expression of matrix metalloproteinases (MMPs) and heparinases, which degrade syndecan-1 (SDC-1) and HS, while oxidative stress disrupts HA-CD44 binding, leading to increased capillary leakage and neutrophil adhesion

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The following table summarizes the primary findings from studies on this compound