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CD8 + T cells of the knockout mice were intrinsically defective in balancing homeostasis in the peripheral environment, implicating GPX4 is required for T cell-regulated immune responses (Matsushita et al., 2015)

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A spectrophotometer was used to measure the SOD activity by keeping an eye on how well it stopped the reduction of nitroblue tetrazolium (NBT) at 560 nm 18

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