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5.2.2 Quercetin and isoquercetin Quercetin (QCT), a plant pigment and potent antioxidant flavonol, predominantly found in onions, grapes, berries, cherries, broccoli, and citrus fruits, serves as a versatile antioxidant known for its protective capacity against tissue damage caused by various drug toxicities (Wang Y

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In Long COVID, oxidative stress may be driven by: persistent immune activation mitochondrial dysfunction mast cell activation (MCAS) chronic inflammation autonomic nervous system dysregulation psychological stress (PTSD, illness trauma) Even everyday factors can worsen the burden: travel overexertion poor sleep emotional stress Supporting the Body Against Oxidative Stress While research is ongoing, strategies that may help reduce oxidative stress include: Foundational Support Anti-inflammatory nutrition Adequate hydration Sleep optimization Stress reduction Nervous System Regulation Breathwork Pacing strategies Reducing overstimulation Nutritional & Clinical Considerations Antioxidant support (as clinically appropriate) Mitochondrial support Addressing histamine and MCAS if present Always consult with a qualified provider before starting new treatments or supplements

The synthesis of substances with bioactive properties is not common for all plant species