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RA-synovium-derived MSCs have impaired mitochondrial transfer to Th17 cells, which may be a key reason for the persistent inflammatory response in RA synovial tissues (79, 80)

Splitting vials across titration phases Some researchers reconstitute their 10 mg vial at a higher concentration (5 mg/mL with 2 mL water) for the later phases when precision is less critical and injection volume matters more

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