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THMD4 is characterized by episodic encephalopathy and weakness, which often presents following a viral infection or febrile illness in childhood

Proteomic analysis of extracellular vesicles released from heat-stroked hepatocytes reveals promotion of programmed cell death pathway

These results inform dosing decisions because they show that higher doses generally produce more weight loss, but the incremental benefit between 10 mg and 15 mg is smaller than between 5 mg and 10 mg

Accordingly, we have recently reported that plantaris muscle from the same pravastatin treated mice model presented mild mitochondrial oxidative stress and higher sensitivity to Ca 2+ -induced MPT ( in vivo supplementation with two distinct antioxidants, CoQ10 and creatine