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Proponents of these laws say they carry a significant public health benefit, as smoking causes more than 480,000 deaths per year in the U.S., according to the Centers for Disease Control and Prevention (CDC)

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Many SHS studies utilize cotinine, the primary metabolite of nicotine, as the biomarker of choice for assessing smoke exposure because of its specificity and longer half-life than nicotine 7,10,11,12,13,14,15,16,17