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doi: 10.3389/fimmu.2025.1530262 Received 18 November 2024 Accepted 07 January 2025 Published 27 January 2025 Volume 16 - 2025 Edited by Souvick Roy, University of California, San Diego, United States Reviewed by Dainius Characiejus, Vilnius University, Lithuania Ramireddy Bommireddy, Emory University, United States Updates Copyright 2025 Yoon, Carvajal, Graboyes, Kaczmar, Albergotti, Kejner, Troob, Philipone, Anoma, Armeson, Hill, Richardson, Woods, Chera, Nourollah-Zadeh, Lee, Pandruvada, Kourtidis, Kingsley, OQuinn, Mills, Jordan, Spencer, Fails, McKee, Zaidi, Brisendine, Horn, Mehrotra, Ogretmen and Newman

Nurse practitioners have an obligation to balance the need for effective pain management with their obligation to give patients the tools they will need to minimize potential long-term adverse effects